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If you are registering a .BIO domain and you are a producer, a transformer, or a retailer in the field of agriculture, food, and farming and plan to use your .BIO for a website related to organics, you have to commit to not undermining the Principles of Organic Agriculture (POA) as formulated by International Federation of Organic Agricultural Movements (IFOAM), which is a partner of the .BIO Registry. (The four POA are health, ecology, fairness, and care.) In addition, you must abide by any regulations in force in the relevant markets where organic products are presented and promoted.
By purchasing your .BIO domain, you are agreeing to these requirements.
If you do not plan to use your .BIO domain for an organic farming or food related website, there are no restrictions.